JRaviLab
JRaviLab
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Computational approaches for understanding host–pathogen biology
Conservation and modularity in the pan-bacterial psp stress response system
An integrative computational evolutionary approach to accelerate the discovery of molecular targets in prevalent under-studied pathogens
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Bacterial Stress Response
Studying stress response systems using molecular evolution and phylogenetics.
Using computational appraches to understand host-pathogen biology
Variations on a theme: evolution of the phage-shock-protein system in Actinobacteria
Evolution and Conservation of the Psp Envelope Stress-Response System
Reconstruction and topological characterization of the sigma factor regulatory network of Mycobacterium tuberculosis
Accessory sigma factors, which reprogram RNA polymerase to transcribe specific gene sets, activate bacterial adaptive responses to noxious environments. Here we reconstruct the complete sigma factor regulatory network of the human pathogen …
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